EM235 Beta Glucan

Glucans are polysaccharides, primarily composed of glucose chains that can be occasionally cross-linked and branched. They are found in the cell walls of bacteria, plants, fungi (yeasts and molds), and algae.

Immunomodulatory Properties:
Glucans, specifically (1→3)-ß-D-glucans, act as immunomodulators.
They bind to and activate various immune cells, including NK cells, neutrophils, monocytes, and macrophages.
Glucans are thought to attach to a range of cells, including fibroblasts and endothelial cells.

Biological Actions:
Glucans induce the production of cytokines, which play a crucial role in inflammation.
They are associated with processes such as nitric oxide generation, complement cascade activation, and activation of lymphocytes and macrophages.
Studies suggest that endotoxin and glucan can work together to boost the inflammatory response, and this combination has been explored in the treatment of certain conditions.